Title

A 33 yo G2P0 presents for pre-conception counseling. She has a history of a pregnancy loss at 11 weeks after a normal 10 week ultrasound as well as a history of a 16 week pregnancy loss in a fetus with trisomy 13. You notice that she tested positive for anti-beta2-glycoprotein IgG 4 months ago and again last week. She has no history of thrombosis. Her mother had venous thromboembolism at age 65. The clinical history that supports the diagnosis of antiphospholipid syndrome in this patient is: